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NFL Week 1 Odds: Let the Games Begin!

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Jordan Love #10 of the Green Bay Packers warms up prior to the game against the Chicago Bears at Soldier Field on December 04, 2022. Michael Reaves/Getty Images/AFP

The NFL officially released the 2023 schedule back in May and with a grand total of 18 weeks waiting to be analyzed, there is only one place to start. That’s right, we kickstart the 2023 NFL regular season with the odds for Week 1. 

After the off-season drama surrounding the Aaron Rodgers trade, Lamar Jackson’s extension and the ups and downs of the NFL draft, we finally have the answers to some pressing questions.

But it all begins on Thursday, September 7, as the defending Super Bowl champs, the Kansas City Chiefs, host the Detroit Lions in what promises to be a high-scoring affair as two of the best offenses from last season go head-to-head.

The line in this game dropped quite a bit on Tuesday afternoon, going from -6½ to as low as -4½ after it was reported that TE Travis Kelce (knee) will miss the game due to injury.

Keep in mind the premier U.S. online betting sites to place your wagers during the NFL season.

A New Era

On Sunday, Jordan Love will make his debut as a full-time starter against the Chicago Bears in what promises to be a new era of this historic rivalry as the Bears are favorites for the first time in years. 

Meanwhile, Rodgers will debut for the New York Jets on Monday Night Football against Josh Allen and the Bills. Check out the latest odds below!

NFL Week 1 Odds

Check out the full slate of games below with the latest NFL Week 1 odds.


Detroit Lions vs. Kansas City Chiefs

Thursday, September 07, 2023 – 08:20 PM EDT at GEHA Field at Arrowhead Stadium


Tennessee Titans vs. New Orleans Saints

Sunday, September 10, 2023 – 01:00 PM EDT at Caesars Superdome


Jacksonville Jaguars vs. Indianapolis Colts

Sunday, September 10, 2023 – 01:00 PM EDT at Lucas Oil Stadium


Tampa Bay Buccaneers vs. Minnesota Vikings

Sunday, September 10, 2023 – 01:00 PM EDT at U.S. Bank Stadium


Arizona Cardinals vs. Washington Commanders

Sunday, September 10, 2023 – 01:00 PM EDT at FedExField


San Francisco 49ers vs. Pittsburgh Steelers

Sunday, September 10, 2023 – 01:00 PM EDT at Acrisure Stadium


Cincinnati Bengals vs. Cleveland Browns

Sunday, September 10, 2023 – 01:00 PM EDT at FirstEnergy Stadium


Carolina Panthers vs. Atlanta Falcons

Sunday, September 10, 2023 – 01:00 PM EDT at Mercedes-Benz Stadium


Houston Texans vs. Baltimore Ravens

Sunday, September 10, 2023 – 01:00 PM EDT at M&T Bank Stadium


Green Bay Packers vs. Chicago Bears

Sunday, September 10, 2023 – 04:25 PM EDT at Soldier Field


Philadelphia Eagles vs. New England Patriots

Sunday, September 10, 2023 – 04:25 PM EDT at Gillette Stadium


Los Angeles Rams vs. Seattle Seahawks

Sunday, September 10, 2023 – 04:25 PM EDT at Lumen Field


Miami Dolphins vs. Los Angeles Chargers

Sunday, September 10, 2023 – 04:25 PM EDT at SoFi Stadium


Las Vegas Raiders vs. Denver Broncos

Sunday, September 10, 2023 – 04:25 PM EDT at Empower Field at Mile High


Dallas Cowboys vs. New York Giants

Sunday, September 10, 2023 – 08:20 PM EDT at MetLife Stadium


Buffalo Bills vs. New York Jets

Monday, September 11, 2023 – 08:15 PM EDT at MetLife Stadium


Weekly NFL Odds Previews